The Construction of Analogy-Based Research Programs
The Construction of Analogy-Based Research Programs
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When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity.Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research pro…
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  • Publisher:
  • Year: 2019
  • Pages: 224
  • ISBN-10: 3837644421
  • ISBN-13: 9783837644425
  • Format: 14.8 x 22.6 x 2 cm, minkšti viršeliai
  • Language: English

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When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity.
Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.

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  • Author: Rebecca Mertens
  • Publisher:
  • Year: 2019
  • Pages: 224
  • ISBN-10: 3837644421
  • ISBN-13: 9783837644425
  • Format: 14.8 x 22.6 x 2 cm, minkšti viršeliai
  • Language: English English

When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity.
Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.

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